Leonard P. Freedman, PhD

Leonard P. Freedman

Biochemistry and Molecular Biology
Professor
Vice Dean for Research, Jefferson Medical College

Mailing Address

1025 Walnut Street, 100 College
Philadelphia, Pennsylvania 19107
United States

Contact Information

Phone: 215-955-2012
leonard.freedman@jefferson.edu

Education:
Ph.D. University of Rochester, Molecular Genetics, 1985
B.A. Kalamazoo College, Biology, 1980

Biography:
Leonard P. Freedman, Ph.D. is Vice Dean for Research and Professor of Biochemistry and Molecular Biology at Jefferson Medical College, Thomas Jefferson University. As Vice Dean, Dr. Freedman is responsible for advancing the medical college's research mission by developing a clear, coordinated strategy that drives the effective integration of the clinical/educational expertise on campus with Jefferson's basic and clinical research faculty, as well as initiate strategic alliances with various medical centers, universities and other research entities, such as the DHSA and the DVICTS CTSA. Dr. Freedman most recently served as vice president of Discovery for Women's Health and Musculoskeletal Therapies at Wyeth Research. There he directed a group of 125 scientists charged with the discovery of new chemical and bio-therapeutic entities in women's health. Prior to his role at Wyeth, he was the executive director for the Department of Molecular Endocrinology at Merck Research Labs, as well as adjunct professor of Medicine in the Division of Endocrinology at the University of Pennsylvania.

Dr. Freedman is a recognized leader in the field of nuclear hormone receptors. Early in his career he joined the laboratory of Dr. Keith Yamamoto, one of the world's leading molecular endocrinologists and focused his research on understanding the molecular mechanisms by which glucocorticoid hormones regulate gene transcription. Dr. Freedman subsequently joined the faculty in Cell Biology & Genetics at Memorial Sloan-Kettering Cancer Center and Cornell University Medical College, where he rose to tenured Full Professor. Dr. Freedman's lab studied the biological roles of vitamin D3 and retinoid receptors in myeloid cells in the context of growth inhibition and differentiation. His lab also defined important new mechanisms by which nuclear receptors mediate transcriptional regulation.

Dr. Freedman has received several research awards, including the Boyer Research Award for Biomedical Research, and was the recipient of numerous grants, including a MERIT award from the National Institute of Diabetes and Digestive and Kidney Diseases. He was also the 2002 recipient of the Ernst Oppenheimer Award from The Endocrine Society.

Dr. Freedman earned a bachelor of arts degree in Biology from Kalamazoo College, and his master of science and Ph.D. in Molecular Genetics from the University of Rochester. He is a member of the American Society for Microbiology, American Society for Biochemistry & Molecular Biology, The Endocrine Society, American Society of Bone and Mineral Research and the New York Academy of Science. He has published extensively and served on numerous scientific review panels. Dr. Freedman has served on the editorial board of Molecular Endocrinology, Endocrinology and Endocrine Reviews, and has also been an editor of Molecular and Cellular Biology for the past eight years.

RECENT PRESS

Achieving great things.

2010 DHSA Research Conference Coverage
May 5, 2010--More than 275 people from the health sciences research and education community turned out for the 2010 Delaware Health Sciences Alliance Conference on Tuesday, May 4, to share research and explore issues in health care.
UD and Nemours/Alfred I. duPont Hospital to partner on bone disorder study
April 15, 2010--In search of a new treatment for the debilitating disease osteogenesis imperfecta (OI), a team of researchers from the University of Delaware and Nemours/Alfred I. duPont Hospital for Children is initiating a two-year study exploring the use of an FDA-approved vibration platform in children with OI.
Delaware Health Sciences Alliance awards two pilot projects
April 1, 2010--Two pilot projects funded by the Delaware Health Sciences Alliance (DHSA) under its second competition focus on identifying cutting-edge cancer therapies, and creating the bioinformatics framework that will facilitate translational research among the alliance members.
Transforming the Region's Healthcare
March, 2010--An article in the March edition of Select Greater Philadelphia's "Momentum" discusses how the DSHA is drawing on the collective resources of its partner members - including the health sciences campus to be developed by the University of Delaware at the former Chrysler site - to revolutionize healthcare research and education in the region.

National experts to speak at Delaware Health Sciences Alliance research conference
Tuesday, February 18, 2010--The Delaware Health Sciences Alliance (DHSA) will host its second annual research conference on May 4 at Christiana Care Health System's John H. Ammon Medical Education Center on the Christiana Hospital Campus.

UD health sciences dean to lead partnership programs
December 14, 2009--Kathy Matt, dean of the College of Health Sciences at the University of Delaware, has been appointed to leadership positions in two partnership programs that she sees as key to promoting health research and education in Delaware.
Older adults with cancer, caregivers focus of $600,000 research grant
Dec. 11, 2009--A team that includes two researchers from the University of Delaware's School of Nursing -- Paula Klemm, professor of nursing, and Veronica Rempusheski, the Jeanne K. Buxbaum Chair of Nursing Science -- has been awarded a two-year, $600,000 grant to conduct research aimed at supporting older adults affected by cancer and their caregivers in Delaware.
DHSA takes center stage at UD Trustees meeting
December 9, 2009--The University of Delaware's Board of Trustees got a firsthand look at the largest single property acquisition in the history of the institution during its semiannual meeting, held Tuesday, Dec. 8, at the former Chrysler assembly plant on South College Avenue in Newark.
Christiana Care's Dr. Petrelli to share cancer success story at national surgeons' conference
November 11, 2009--Christiana Care's pioneering role in significantly reducing Delaware's cancer rate will be in the national spotlight at a prestigious medical conference.