Nemours Biomedical Research

Thomas H. Shaffer, MS.E, PhD

Director of Nemours Research Lung Center
Professor of Pediatrics
Thomas Jefferson School of Medicine

Alfred I. duPont Hospital for Children
Nemours Biomedical Research
1600 Rockland Road
Wilmington, DE 19803

Phone: (215) 707-3239
E-mail: tshaffer@nemours.org

Education
Ph.D., Applied Mathematics, Drexel University, 1972
M.S., Applied Mathematics, Drexel University, 1970
B.S., Mechanical Engineering & Mathematics, Drexel University, 1968

Biography:
Thomas H. Shaffer, MS.E., Ph.D., is Professor Emeritus of Physiology and Pediatrics.  He also holds the position of Professor of Pediatrics at Thomas Jefferson Medical College.  Dr. Shaffer received his doctorate from Drexel University in Philadelphia, Pennsylvania, did postdoctoral work at the University of Pennsylvania School of Medicine, and has been a member of the faculty of the Temple University School of Medicine since 1976. Dr. Shaffer has 28 years of experience as an active scientist in pulmonary research with special attention to the needs of the neonatal and pediatric populations.  Dr. Shaffer’s revolutionary work with the use of perfluorochemicals for liquid ventilation for respiratory distress syndrome, blood substitutes and imaging is known worldwide, and he is considered an international expert in this field.  In addition, he is renown for his work in developmental airway physiology and clinical pulmonary function evaluation in neonates.

Since 1974, Dr. Shaffer has been continuously supported by NIH grants (17) and academic, corporate and private institutional awards (42 total).  His early NIH grants were awarded during a period when corporate sponsors were not readily supporting work in his area of interest, and the resultant science acted as a catalyst for procuring many other grants from the private and corporate sectors.  The excellence of his corporate-sponsored research has resulted in 12 licensed patents.   In September 2004, Dr. Shaffer was awarded a Center for Biomedical Research Excellent (COBRE) grant from the National Institutes of Health for the development of a Center for Pediatric Research at the Alfred I. duPont Hospital for Children in Wilmington, Delaware.  He serves as the Director of the new Center and administers its staff, revenues and research.  Dr. Shaffer clearly understands translational research, having moved multiple intellectual properties from the bench top to the clinic and on to industry.

Dr. Shaffer’s contribution to the literature has been significant.  He has published 67 book chapters, 220 peer-reviewed manuscripts (with another 20 in review or in press), and 460 abstracts.  His clinical manuscripts have been published in Lancet, The New England Journal of Medicine, the Journal of Pediatrics, Pediatrics, Critical Care Medicine and many more highly respected and well-read periodicals.  In addition, he has published basic science manuscripts in the Journal of Applied Physiology, the American Journal of Physiology, and the American Journal of Circulatory Research.  He serves on the Editorial Boards of three scientific journals and is a journal reviewer for another 22 publications.

RECENT PRESS

Achieving great things.

2010 DHSA Research Conference Coverage
May 5, 2010--More than 275 people from the health sciences research and education community turned out for the 2010 Delaware Health Sciences Alliance Conference on Tuesday, May 4, to share research and explore issues in health care.
UD and Nemours/Alfred I. duPont Hospital to partner on bone disorder study
April 15, 2010--In search of a new treatment for the debilitating disease osteogenesis imperfecta (OI), a team of researchers from the University of Delaware and Nemours/Alfred I. duPont Hospital for Children is initiating a two-year study exploring the use of an FDA-approved vibration platform in children with OI.
Delaware Health Sciences Alliance awards two pilot projects
April 1, 2010--Two pilot projects funded by the Delaware Health Sciences Alliance (DHSA) under its second competition focus on identifying cutting-edge cancer therapies, and creating the bioinformatics framework that will facilitate translational research among the alliance members.
Transforming the Region's Healthcare
March, 2010--An article in the March edition of Select Greater Philadelphia's "Momentum" discusses how the DSHA is drawing on the collective resources of its partner members - including the health sciences campus to be developed by the University of Delaware at the former Chrysler site - to revolutionize healthcare research and education in the region.

National experts to speak at Delaware Health Sciences Alliance research conference
Tuesday, February 18, 2010--The Delaware Health Sciences Alliance (DHSA) will host its second annual research conference on May 4 at Christiana Care Health System's John H. Ammon Medical Education Center on the Christiana Hospital Campus.

UD health sciences dean to lead partnership programs
December 14, 2009--Kathy Matt, dean of the College of Health Sciences at the University of Delaware, has been appointed to leadership positions in two partnership programs that she sees as key to promoting health research and education in Delaware.
Older adults with cancer, caregivers focus of $600,000 research grant
Dec. 11, 2009--A team that includes two researchers from the University of Delaware's School of Nursing -- Paula Klemm, professor of nursing, and Veronica Rempusheski, the Jeanne K. Buxbaum Chair of Nursing Science -- has been awarded a two-year, $600,000 grant to conduct research aimed at supporting older adults affected by cancer and their caregivers in Delaware.
DHSA takes center stage at UD Trustees meeting
December 9, 2009--The University of Delaware's Board of Trustees got a firsthand look at the largest single property acquisition in the history of the institution during its semiannual meeting, held Tuesday, Dec. 8, at the former Chrysler assembly plant on South College Avenue in Newark.
Christiana Care's Dr. Petrelli to share cancer success story at national surgeons' conference
November 11, 2009--Christiana Care's pioneering role in significantly reducing Delaware's cancer rate will be in the national spotlight at a prestigious medical conference.